Disorders of Ventilation and Gas Exchange Case Study
Disorders of Ventilation and Gas Exchange Case Study
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Disorders of Ventilation and Gas Exchange Case Study
Ashman is an inflammatory disease of the respiratory tract that is common in children and adolescents. Grossman and Porth (2014) affirm that asthma leads to chronic illness among pediatrics. Conversely, Hossny et al. (2016) demonstrate that asthma causes high morbidity and contributes to school absenteeism, mortality, acute exacerbations, and hospitalization. The purpose of this assignment is to provide an analysis of a 5-year-old with asthma in the last two years. Specifically, the essay will highlight the device of action of corticosteroid inhalers and the way it differs from β 2 –agonist inhalants. The discussion will also present the basis of physical fatigue and severe asthma while focusing on physiological events witnessed during an attack. In addition, the paper discusses how the body recompenses for increased CO2 and the effect of hypercapnia on the central nervous system (CNS).
Question 1
What is the mechanism of action of a corticosteroid inhaler?
Persistent asthma requires anti-inflammatory management, and the most effective way is by using inhaled corticosteroids
Disorders of Ventilation and Gas Exchange Case Study
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References
Bush, A. (2019). Pathophysiological mechanisms of asthma. Frontiers in Pediatrics, 7. doi: 10.3389/fped.2019.00068
Grossman, S. C., & Porth, C. M. (2014). Porth’s pathophysiology, 9th ed. Philadelphia: Wolters Kluwer Health/ Lippincott Williams and Wilkins.
Hossny, E., Rosario, N., Lee, B. W., Singh, M., El-Ghoneimy, D., Soh, J. Y., & Le Souef, P. (2016). The use of inhaled corticosteroids in pediatric asthma: update. World Allergy Organization Journal, 9(1), 26. doi: 10.1186/s40413-016-0117-0
Hossny, E., Rosario, N., Lee, B. W., Singh, M., El-Ghoneimy, D., Soh, J. Y., & Le Souef, P. (2016). The use of inhaled corticosteroids in pediatric asthma: update. World Allergy Organization Journal, 9(1), 26. doi: 10.1186/s40413-016-0117-0
Patel, S., Miao, J. H., & Majmundar, S. H. (2020). Physiology, Carbon Dioxide Retention. In StatPearls [Internet]. StatPearls Publishing.
Van Herck, M., Spruit, M. A., Burtin, C., Djamin, R., Antons, J., Goërtz, Y. M., … & Thong, M. S. (2018). Fatigue is highly prevalent in patients with asthma and contributes to the burden of disease. Journal of Clinical Medicine, 7(12), 471. doi: 10.3390/jcm7120471